Mondo Knows Facts

Adenosine builds up in the brain while awake

This breakdown product of cellular energy accumulates and increases the drive to sleep As brain cells burn ATP through the day, adenosine accumulates in the fluid around them. It binds receptors that dampen arousal circuits, creating what researchers call sleep pressure. Levels fall during sleep, partly because the compound is cleared and rebuilt into ATP. It sits in Mondo's human body collection, one of 200 facts that each trace back to the reference below.

Where this comes from

Sleep Foundation

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Tags: sleep, adenosine, brain

Adenosine builds up in the brain while awake: the short answers

Where does this come from, and can I check it?
This breakdown product of cellular energy accumulates and increases the drive to sleep. The figure is taken from Sleep Foundation, which is linked in full on this page. Every fact on Mondo Knows names its source rather than repeating an unsourced claim.
Is this really a human body fact?
Yes. It sits on the Human Body shelf, one of 2,600 sourced facts grouped into space, animals, the human body, history, science and more. Category pages collect every fact in the same field.
What else can I read about it?
The links under the fact point to a quiz, game, puzzle or calculator on the same subject, and the shelf below shows related facts. The wording here is original, and quoted phrases are marked as quotations.