Where does this come from, and can I check it?

Leptin is released in proportion to body fat and signals satiety to the hypothalamus. The figure is taken from NIDDK, which is linked in full on this page. Every fact on Mondo Knows names its source rather than repeating an unsourced claim.

Is this really a human body fact?

Yes. It sits on the Human Body shelf, one of 2,600 sourced facts grouped into space, animals, the human body, history, science and more. Category pages collect every fact in the same field.

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The links under the fact point to a quiz, game, puzzle or calculator on the same subject, and the shelf below shows related facts. The wording here is original, and quoted phrases are marked as quotations.

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Fat tissue signals the brain through leptin

Leptin is released in proportion to body fat and signals satiety to the hypothalamus Adipose tissue secretes leptin continuously, so its level reflects how much fat the body holds. The hypothalamus reads that signal as a measure of available energy and adjusts appetite and energy use. When fat stores fall sharply, leptin drops and hunger circuits become more active. It sits in Mondo's human body collection, one of 200 facts that each trace back to the reference below.

Where this comes from

NIDDK

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Tags: leptin, fat, appetite

Fat tissue signals the brain through leptin: the short answers

Where does this come from, and can I check it?: Leptin is released in proportion to body fat and signals satiety to the hypothalamus. The figure is taken from NIDDK, which is linked in full on this page. Every fact on Mondo Knows names its source rather than repeating an unsourced claim.
Is this really a human body fact?: Yes. It sits on the Human Body shelf, one of 2,600 sourced facts grouped into space, animals, the human body, history, science and more. Category pages collect every fact in the same field.
What else can I read about it?: The links under the fact point to a quiz, game, puzzle or calculator on the same subject, and the shelf below shows related facts. The wording here is original, and quoted phrases are marked as quotations.