Mondo Knows Facts
Mast cells release histamine during allergic reactions
These tissue-resident immune cells store histamine in granules ready for release Mast cells sit in skin, airways and gut lining, packed with granules of histamine and other mediators. When an antibody bound to their surface meets an allergen, the cell empties those granules within seconds. Histamine widens small blood vessels and makes them leaky, producing swelling, redness and itching. It sits in Mondo's human body collection, one of 200 facts that each trace back to the reference below.
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Facts that can change over time are reviewed and updated. If something here looks wrong, Mondo would rather know than be confidently incorrect.
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Tags: histamine, allergy, mast-cells
Mast cells release histamine during allergic reactions: the short answers
- Where does this come from, and can I check it?
- These tissue-resident immune cells store histamine in granules ready for release. The figure is taken from NHS, which is linked in full on this page. Every fact on Mondo Knows names its source rather than repeating an unsourced claim.
- Is this really a human body fact?
- Yes. It sits on the Human Body shelf, one of 2,600 sourced facts grouped into space, animals, the human body, history, science and more. Category pages collect every fact in the same field.
- What else can I read about it?
- The links under the fact point to a quiz, game, puzzle or calculator on the same subject, and the shelf below shows related facts. The wording here is original, and quoted phrases are marked as quotations.