Mondo Knows Facts
CRISPR originated as a bacterial defense against viral infections
Bacteria store fragments of viral DNA to recognise and slice invading viruses
CRISPR sequences were first discovered in bacteria as an adaptive immune mechanism designed to defeat bacteriophage viruses. Bacteria capture snippets of invading viral DNA and store them within their own genome to guide Cas nucleases to cut matching viral sequences during future attacks. Molecular biologists adapted this system into a revolutionary genome editing tool.
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Tags: biology, crispr, genetics
CRISPR originated as a bacterial defense against viral infections: the short answers
- Where does this come from, and can I check it?
- Bacteria store fragments of viral DNA to recognise and slice invading viruses. The figure is taken from Nobel Prize, which is linked in full on this page. Every fact on Mondo Knows names its source rather than repeating an unsourced claim.
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